DDIS-17. MULTI-LEVEL DRUG DEVELOPMENT PIPELINE FOR THE DISCOVERY OF TUMOR MICROTUBE TARGETING DRUGS

Candidiasis drug discovery and development: new approaches targeting virulence for discovering and identifying new antifungal drugs

Professor of Biology University of Texas at San Antonio Candidiasis Drug Discovery and Development: New Approaches Targeting Virulence for Discovering and Identifying New Antifungal Drugs Targeting pathogenetic mechanisms rather than essential processes represents a very attractive alternative for the development of new antibiotics. This may be particularly important in the case of antimycotics...

DEVELOPMENT OF NEW DRUGS FOR TB CHEMOTHERAPY Analysis of the current drug pipeline

***Removed from the Issue*** Application of Cell-Based Assay Systems for the Early Screening of Human Drug Hepatotoxicity in the Discovery Phase of Drug Development

Antimalaria Drug Development & Pipeline

Artemisin traditionally cleave the peroxide bond by Fe(II) found in heme proteins, thus generating toxic oxygen radicals. Synthetic peroxides, thus are proving to be useful substitutes for artemisinin. The first-generation ozonide OZ277, known as arterolane [1], has been found to inhibit the growth of chloroquine-resistant (K1) and chloroquine sensitive (NF54) parasite strains. In 2012, the com...

***Removed from the Issue*** Application of Cell-Based Assay Systems for the Early Screening of Human Drug Hepatotoxicity in the Discovery Phase of Drug Development